Michael Kearse — Assistant Professor, Principal Investigator
BS with Distinction, Penn State University PhD, Lehigh University Postdoc, University of Michigan (NIH F32 Kirschstein NRSA Fellow) Postdoc, University of Pennsylvania (NIH K99/R00 Pathway to Independence Award)
Research Interests: ribosomes, mechanisms & regulation of mRNA translation, RNA-based mechanisms of human disease, collaborative science.
Out of Lab Interests: spending time with my wife and our two young kids, dark roast coffee, BIG10 college football, the Columbus Crew.
Caleb Clark — Discovery PREP Postbac Research Scholar
BS, Morehead State University OSU College of Medicine Discovery PREP (2024-2025)
"I enjoy rock climbing, hiking, and traveling whenever possible. I'm most excited to learn more about RNA biology."
Morgan Buchman — PhD Student
buchman.38@buckeyemail.osu.edu
BS, Grand Valley State University Ohio State Biochemistry Program, The Ohio State University (entered 2023)
“I love all animals (especially dogs) and traveling. I also like to read, watch football and explore the city.”
Carter Flora — Undergraduate Research Student
Class of 2027 Major: Biomedical Science (College of Medicine)
“I'm very excited to learn more about RNA biology and build relationships with you and other lab members!”
Outside of Lab Interests: I enjoy everything outdoors — sports, hiking, and walking my dog. I recently became an intermural soccer champion!
Chloe Reavill — Rotating PhD Student
BS, University of California—Santa Barbara Ohio State Biochemistry Program, The Ohio State University (entered 2024)
“I am stoked about RNA biology! Some of my hobbies include trying restaurants and breweries around Columbus, training for half marathons, and getting too invested in TV shows.”
Paul Russell — PhD Candidate
russell.699@buckeyemail.osu.edu
BS, University of Michigan MS, University of Michigan Ohio State Biochemistry Program, The Ohio State University (entered 2019)
CA Fellowship — 2019-2020 academic year CMBP Fellowship — 2020-2021 and 2021-2022 academic years Center for RNA Biology Fellowship — 2022-2023 academic year Center for RNA Biology Travel Award — 2024
“I'm a proud Michigan alum and sports fan just trying to survive in the heart of Buckeye nation.”
Research Interests: ribosomes, uORFs, translational control, mRNA stability , ribosome turnover and decay
Outside of Lab Interests: Philadelphia sports, Michigan football/basketball, Buckeyes losing in any sports (click here for reference), binging terrible dating shows on Netflix, and marathon training.
Julia Warrick — PhD Candidate
warrick.45@buckeyemail.osu.edu
BS, Marryville College Biomedical Sciences Graduate Program, The Ohio State University (entered 2021)
Center for RNA Biology Fellowship — 2023-2024 academic year Center for RNA Biology Travel Award — 2024
“I am a Maryville College alum, and I love to read, paint, and watch football. I also love to hike and buy new plants.”
Addie and Lincoln (now and then)
Junior members of the lab that contribute to the entropy of the lab’s staff office during time points that spill over into the weekends.
Out of Lab Interests: growing up too fast, rock climbing, driving Mike crazy by watching the same Disney movies all the time, ice cream, the Columbus Crew, and family night at the Columbus Clippers.
Max
The Cadillac of all plate readers with all the bells and whistles. It does everything for absorbance-, fluorescence-, luminescence-, FRET-, BRET-based assays.
Funke
A dedicated fluorometer with enhanced fluorescence detection and polarization capabilities. Although filter-based (instead of a monochromator), the Tecan Spark is able to measure fluorescence (intensity and polarization) at low and sub nM concentrations.
Frac/Frank/The Expensive Big Red Box
Originally hailing from New Brunswick, Canada via the folks at Biocomp, Frac, along with a completely digital and awesome Triax flow cell and perfectly-timed automated fraction collector, is uniquely capable of simultaneous UV absorbance and fluorescence detection. Perfect for ribosome fractionation and polysome profiling.
Join us!
We are always looking to hear from students and postdocs looking to learn and contribute to our team. If you are interested in RNA biology, translation, and human disease, learn more here or contact us at michael.kearse@osumc.edu.
Lab Alumni
Mia Ashriem (class of 2024); ashriem.1@buckeyemail.osu.edu — Undergraduate Honors Research Student, 2022-2024
Currently pursuing a PhD in Molecular, Cellular, and Developmental Biology at Ohio State (entered August 2024).
Lainie Boyle (and Ranger); lainie.boyle@biochem.utah.edu — Research Assistant, 2020-2021
Currently a PhD candidate in Dr. Brenda Bass’ lab at the University of Utah.
Nicholas Forsyth ; forsyth1@kenyon.edu — Visiting Summer Research Student from Kenyon College, 2024
Currently finishing his BS in Chemistry (class of 2026) before applying for PhD programs.
Daisy Grove, PhD; grove.288@buckeyemail.osu.edu — PhD student/candidate, 2019-2024
Dissertation Title: Characterization of the inhibitory function of eIF2A in mRNA translation
OSBP Plenary Speaker at the OSU LS-IGP Symposium — 2023
Currently a postdoctoral researcher at Northern Kentucky University.
Sarah Hoffmann-Weitsman; sehoffmannweits@knox.edu — Visiting Summer Research Student from Knox College, 2022
Currently pursuing a PhD at WashU in St. Louis (entered August 2024).
Daniel Levine (class of 2023); levine.1789@buckeyemail.osu.edu — Undergraduate Research Student, 2021-2023
After teaching English in Spain for a year, Daniel is currently in medical school at NYU Grossman Long Island School of Medicine and will focus on primary care & internal medicine.
Kenzie Scarpitti, PhD; scarpitti.36@buckeyemail.osu.edu — PhD Student/Candidate, 2019-2024
Dissertation Title: Mechanisms of translational control by the fragile X protein, FMRP
University Fellowship — 2019-2020 academic year Center for RNA Biology Fellowship — 2020-2021 academic year Johnson Academic Excellence Award — 2022
Currently pursuing postdoctoral and industry research.
Darren Webb; webb.799@buckeyemail.osu.edu — Research Assistant, 2022-2023
Currently pursuing research in industry before applying to graduate shcool.
Elly Yoder (class of 2024); yoder.459@buckeyemail.osu.edu — Undergraduate Research Student, 2021-2024
Currently pursuing a professional career in the medical field.
Former PhD Rotation Students Callie Barber; callie.barber@osumc.edu — Spring 2024 Madeline Burghaze; burghaze.1@buckeyemail.osu.edu — Autumn 2023 Pallavi Chandna; chandna.3@buckeyemail.osu.edu — Summer 2022 MK McCulloch; mcculloch.68@buckeyemail.osu.edu — Autumn 2023 Runwei Zhou; zhou.4224@buckeyemail.osu.edu— Spring 2024